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4-Hydroxybenzyl alcohol
CAS No. 623-05-2
4-Hydroxybenzyl alcohol ( —— )
产品货号. M18916 CAS No. 623-05-2
4-Hydroxybenzylool 在脑缺血性损伤中表现出有益作用，通过 PI3K/Akt 途径上调 Nrf2、Prdx6 和 PDI 表达而具有神经保护作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | ￥235 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称4-Hydroxybenzyl alcohol
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述4-Hydroxybenzylool 在脑缺血性损伤中表现出有益作用，通过 PI3K/Akt 途径上调 Nrf2、Prdx6 和 PDI 表达而具有神经保护作用。
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产品描述4-Hydroxybenzyl alcohol exhibits beneficial effects in cerebral ischemic injury, has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt pathway. 4-Hydroxybenzyl alcohol inhibit the development of new blood vessels by targeting multiple mechanisms of the angiogenic process, may as a promising candidate for the establishment of anti-angiogenic treatment strategies in cancer therapy.
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体外实验4-Hydroxybenzyl alcohol inhibits proliferation of eEND2 cells and suppresses the migration of eEND2 cells, accompanied by inhibition of actin filament reorganization.4-Hydroxybenzyl alcohol induces apoptotic death of tumor cells.
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体内实验4-Hydroxybenzyl alcohol possesses antiangiogenic, anti-inflammatory and anti-nociceptive activity possibly via its down-regulating activity on NO production. 4-Hydroxybenzyl alcohol (200 mg/kg) efficiently inhibits growth and angiogenesis of developing tumors.4-Hydroxybenzyl alcohol ameliorates ischemic injury induced by transient focal cerebral ischemia in rats, and this neuroprotective effect may be partly related to attenuate apoptosis pathway.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域Others-Field
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适应症——
化学信息
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CAS Number623-05-2
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分子量124.14
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分子式C7H8O2
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纯度>98% (HPLC)
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溶解度DMSO : 100 mg/mL; 805.54 mM
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SMILESC1=CC(=CC=C1CO)O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Laschke MW,et al.4-hydroxybenzyl alcohol: a novel inhibitor of tumor angiogenesis and growth. 2013 Jul 19;93(1):44-50.
产品手册
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